(8α,13α,14β,17Z)-16β-Acetoxy-3α-hydroxy-9,11-didehydro-29-nor-5α-dammara-17(20),24-dien-21-oic acid - Names and Identifiers
Name | 9,11-Anhydro Fusidic Acid
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Synonyms | 9,11-Anhydrofusidic acid 9,11-Anhydro Fusidic Acid Fusidic Acid EP Impurity L Fusidic Acid Impurity L(EP) Sodium Fusidate EP Impurity L (8α,13α,14β,17Z)-16β-Acetoxy-3α-hydroxy-9,11-didehydro-29-nor-5α-dammara-17(20),24-dien-21-oic acid (3α,4α,8α,13α,14β,16β,17Z)-16-(Acetyloxy)-3-hydroxy-29-nordaMMara-9(11),17(20),24-trien-21-oic Acid (2Z)-2-[(3R,4S,5S,8R,10S,13R,14S,16R)-16-acetyloxy-3-hydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,12,13,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid
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CAS | 74048-41-2
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(8α,13α,14β,17Z)-16β-Acetoxy-3α-hydroxy-9,11-didehydro-29-nor-5α-dammara-17(20),24-dien-21-oic acid - Physico-chemical Properties
Molecular Formula | C31H46O5
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Molar Mass | 498.7 |
Density | 1.13±0.1 g/cm3(Predicted) |
Boling Point | 616.7±55.0 °C(Predicted) |
pKa | 4.05±0.41(Predicted) |
Storage Condition | 2-8°C |
(8α,13α,14β,17Z)-16β-Acetoxy-3α-hydroxy-9,11-didehydro-29-nor-5α-dammara-17(20),24-dien-21-oic acid - Introduction
9,11-Hydro Fusidic Acid (9,11-hydrogenated emodin Acid) is a derivative of emodin. It is a white or almost white crystalline powder with a strong bitter taste. The following is a description of the properties, uses, preparation and safety information of 9,11-hydrogenated emodin acid:
Nature:
-Appearance: White or off-white crystalline powder
-Density: about 1.35 g/cm ^ 3
-Melting Point: about 237-238 ℃
-Solubility: Soluble in alcohol solvent, almost insoluble in water
-chemical properties: 9,11-hydrogenated emodin acid is a carboxylic acid, can occur esterification, acylation and other reactions.
Use:
-Pharmaceutical field: 9,11-hydrogenated emodin acid has antibacterial activity and can be used as a raw material for antibacterial drugs, especially for Staphylococcus aureus, staphylococcus aureus and Actinomycetes have a strong inhibitory effect.
Preparation Method:
- 9,11-Hydrogenated emodin acid can be prepared by carboxylation of emodin. First, the hydroxyl moiety of Emodin is converted to a carboxyl group by acid catalysis, and then deoxygenated by suitable conditions to form 9,11-hydrogenated emodin acid.
Safety Information:
The safety data of -9,11-hydrogenated emodin acid are rarely available, so it is necessary to strictly follow the relevant safety operating procedures when using and handling, such as wearing appropriate personal protective equipment (such as gloves, protective glasses).
-When stored, it should be kept in a dry, well-ventilated place, away from fire and incompatible substances.
- 9,11-Hydrogenated emodin acid is for scientific research and experimental purposes only and should not be used in humans or animals.
-Before using 9,11-hydrogenated emodin acid, it is best to read the relevant safety data sheet and operating manual carefully to ensure safe and correct use.
Last Update:2024-04-09 21:32:49